Related Links
Alpha-1 as Seen
on PBS
Watch the PBS show about Alpha-1.
Symptom Checker
Find out if you are at risk with our symptom checker.
Symptoms of Alpha-1
The following symptoms and conditions may be indications of alpha-1 antitrypsin (AAT) deficiency.1
- Early onset of emphysema (age 45 years or less)
- COPD – emphysema, chronic bronchitis or bronchiectasis
- Family history of any of the following: emphysema/COPD, liver disease or panniculitis
- Asthma with minimal response to medication, inhalers
- Shortness of breath with routine activity
- Cough with or without mucus
- Wheezing
- Liver disease with unknown cause
If you are concerned, ask your doctor if you should be tested for AAT deficiency. For more information about testing, visit the Testing for Alpha-1 section. You may also download a printable version of Should You Be Tested? to share with friends and family you may be concerned about.
References
- Adapted from the American Thoracic Society/European Respiratory Society Statement. Standards for the diagnosis and management of individuals with AAT deficiency. Am J Respir Crit Care Med. 2003;168:818-900.
